He was born at the manse of Cargill on 9 April 1807, and after a distinguished career at the University of Edinburgh, especially in the classes of Sir John Leslie and Professor Wilson, became minister of Ormiston, in Midlothian, in 1833, left the Established Church for the Free Church in 1843, and in 1849 was appointed professor of apologetics and pastoral theology in the New College, Edinburgh, which office he held till his death, 27 March 1868, at his home, 7 Clarendon Crescent, near Dean Bridge.

He took a leading part in various public movements, especially in that which led in 1843 to the separation of the free church from the state, and subsequently in the negotiations for union between the nonconformist presbyterian churches of England and Scotland.

His chief publications were: Rosemary Mitchell asserts: "Bannerman published several theological works: one of the most significant, Inspiration: the Infallible Truth and Divine Authority of the Holy Scriptures (1865), was criticized by the theologian A.

Nevertheless, it sounded a cautious retreat from the fundamentalism of Free Church orthodoxy, as Bannerman dissociated himself from the theory of verbal inspiration and accepted translations (and even paraphrases) as equally valid with the Greek and Hebrew scriptural originals.

[15] A third son, Major General William Burney Bannerman FRSE (1858–1924), married Helen Brodie Cowan Watson, daughter of Robert Boog Watson,[16] and he and his wife are buried with the parents in the north-west section of the Grange Cemetery in Edinburgh.