As of August 2024, Comer's investigation has yet to unearth evidence that Joe Biden was directly involved or profited from his family's business activities.

[2] After Joe Biden ended his 2024 presidential re-election campaign, Comer began an investigation into the new Democratic presidential nominee, Vice President Kamala Harris, and also began an investigation into the new Democratic vice-presidential nominee, Governor Tim Walz.

A year later, he won the Republican nomination for Kentucky's 1st congressional district to succeed Ed Whitfield.

[5] In 2000, Comer was elected to the Kentucky House of Representatives at the age of 27 following the retirement of incumbent Billy Polston.

[27] On August 2, 2014, during the annual Fancy Farm picnic, Comer announced he would seek the Republican nomination for governor of Kentucky in the 2015 election.

[35] In 2016, Comer entered the Republican primary election for the 1st congressional district of Kentucky against two other competitors.

[38] He was sworn in soon after the results were certified, giving him two months' more seniority over the rest of the 2017 freshman class.

During his first few months in office, Comer held several town hall meetings, where he discussed the Congress's early platform.

[45] After the bill passed, he said: "I am proud to support this critical part of President Trump's pro-growth agenda that will fulfill this promise to the American people who have struggled under the weight of Washington bureaucrats for far too long.

[47] The bill was later included in the Agriculture Improvement Act of 2018 and signed into law by President Trump on December 20, 2018.

It also gives local school officials discretion over substitutions for meal components if supply or procurement is disrupted.

[50] After it cleared the House and Senate, President Trump signed the legislation into law on March 18.

He had documents in one location behind a locked door," Florida Democratic congressman Jared Moskowitz aired previously publicly widely distributed footage of large quantities boxes of classified and confidential documents in Mar-a-Lago were haphazardly stored in various places including an unlocked bathroom and on a theater stage.

[59] Comer discussed the impeachment inquiry into Joe Biden in October 2023, stating that "because we have so many documents, and we can bring these people in for [private] depositions or [public] committee hearings, whichever they choose".

[60] In March 2024, Comer declared: "I am preparing criminal referrals as the culmination of my investigation" for the impeachment inquiry into Joe Biden.

"[63] In August 2024, The Washington Post reported that Comer's "investigation quietly sputtered out after no evidence or testimony obtained by congressional Republicans showed that the president was a direct participant in or beneficiary of his family’s business dealings … Comer himself also promised multiple criminal referrals against [Joe] Biden that never materialized.

"[2] After Joe Biden ended his 2024 presidential re-election campaign and Vice President Kamala Harris became the Democratic Party presidential nominee, Comer in August 2024 announced an investigation into Harris' actions in regard to U.S. Customs and Border Protection and the United States-Mexico border, with Comer declaring that it was "unclear what actions, if any, Vice President Harris has taken to fix the border crisis".

[64] Later in August 2024, Comer announced another investigation, this time on the Democratic Party's vice-presidential nominee, Tim Walz, the Governor of Minnesota, as Comer asked the Federal Bureau of Investigation to provide information on Walz in relation to China.

[71] He also opposes banning discrimination based on sexual orientation and gender identity, and voted against the Equality Act in 2019.

[102] In 2020, Comer was criticized for stock trading ahead of the COVID-19 pandemic-related 2020 stock market crash: Comer reportedly dumped shares in Bank of America and purchased shares of online workplace messaging company Slack.

[102] On May 5, 2015, Comer was accused of physical and mental abuse by Marilyn Thomas, a woman he dated while attending Western Kentucky University in 1993.