James Gillespie FRSE (1722–1791) was a Scottish minister and theologian.
[1] He was the son of Rev James Gillespie, minister of Arngask.
In November 1768 the university awarded him an honorary doctorate (DD).
His brother Rev Laurence Gillespie was minister of Auchtermuchty.
Following Isobel's death in 1770, in 1772 he married Jean Fortoun (d.1810) with whom he had at least four more children.