[1][2][3] He works at St. Michael's Hospital in Toronto, and is the strategic director of Toronto-Addis Ababa Academic Collaboration in Emergency Medicine, which has frequently taken him to Ethiopia.

His work for Médecins sans Frontières in Abyei was the focus of his first memoir Six Months in Sudan,[5] which was nominated for, among others, the John Llewellyn Rhys Prize.

[11] He has been praised for highlighting the issue of drug interactions with grapefruit consumption,[12] and encouraging awareness of global health at all levels of university education.

[21] His writing on global issues has appeared in The Washington Post,[22] and The Globe and Mail where he wrote a diary describing the early days of the COVID19 pandemic in Canada.

[24] Maskalyk hosts regular public events on Facebook, where he leads meditation sessions and conversations about a wide rage of topics including sex, alcohol, kindness, existentialism, exercise, economics, computer modelling, and death.

[5] In 2017, Maskalyk released his second autobiographical memoir Life on the Ground Floor, in which he shares stories about his work in emergency departments in Canada, Ethiopia, Cambodia and Bolivia.