O'Toole is a small business owner and a member of the politically influential Plumbers and Pipefitters Local 562 labor union.
As a result of redistricting in 2002, District 68 moved to Barry and Stone counties in southwestern Missouri.
After leaving the legislature, O'Toole served for a time as Democratic director of the Board of Election Commissioners for the City of St. Louis.
He also made an unsuccessful bid for the Democratic nomination for Ward 16 alderman in St. Louis in 2003.
O'Toole resides in Princeton Heights, St. Louis with his wife, Ronda, and three children: Alexandra, Timothy and Katherine.