In 1797, he was in practice as a portrait-painter at 4 York Street, Manchester; shortly afterwards, he moved to London.
On his return, he spent a short time in Glasgow, when he painted a portrait of David Hamilton the architect.
[2] Saxon's portraits show the influence of John Opie.
[2] The portrait of John Clerk of Eldin from 1805 has a background showing a system of naval evolution conceived by Clerk, by William Anderson (1757–1837); it went to the Scottish National Portrait Gallery.
In the same year, he painted a portrait of Sir Walter Scott, which was engraved in stipple by James Heath, as an illustration to The Lady of the Lake (1810).