James T. Rosenbaum (born September 29, 1949) is an American physician-scientist who is Chief of Ophthalmology emeritus at the Legacy Devers Eye Institute, Portland, Oregon, where he held the Richard Chenoweth Chair.

He is recognized for his description of an animal model of uveitis (inflammation inside the eye) resulting from injection of bacterial endotoxin[2] and for more than 600 scholarly publications, mostly related to the intersection between rheumatology and ophthalmology.

From September 1983 to August 1985, he was Director of the Kuzell Institute for Arthritis Research, California Pacific Medical Center, San Francisco.

He rose to become Chief of Arthritis and Rheumatic Diseases and held the Edward E Rosenbaum Professorship in Inflammation Research.

[7] In September 2012 he concurrently became Chief of Ophthalmology at the Legacy Devers Eye Institute, taking emeritus status in August 2019.