He completed his apprenticeship in engraving and then established himself independently, following the dot and stipple style.
His engravings and paintings featured both leading figures of his day and those of previous periods.
After completing an apprenticeship with Mackenzie, he worked for two years under Anthony Cardon, and then established himself independently.
Working mainly on portraits, Thomson was engaged for major illustrated works including Edmund Lodge's Portraits of Illustrious Personages, Fisher's National Portrait Gallery (of Henry Fisher, Son and Jackson, edited by William Jerdan), Horace Walpole's Anecdotes of Painting, Charles Heath's Book of Beauty, Anne Mee's Gallery of Beauties, the Keepsake, the Court Magazine, and Ancient Marbles in the British Museum.
Thomson's single plates included the portraits: By his wife, Diana, whose maiden name was Lloyd, he had two daughters: Eliza and Ann.