Signed to House Anxiety /Marathon Artists, Isaac's debut EP, I Will Be Cold Soon, attracted attention for its near-choral incantations, minimalist jazz tones and post-rock layering.
[6][7] Featuring Jamie in The Guardian's New Music, Michael Cragg praised "Blue Break" for "favouring space and atmosphere over production histrionics".
[8] In the run up to the release of his debut album Couch Baby, Isaac presented the 'Loose Grip' Mixtape, a series of remixes of tracks taken from the album featuring collaborations with Rejjie Snow, King Krule under the moniker Edgar The Beatmaker, Jesse James Solomon, Jadasea, Black Mack, and Mr Malarky.
In March 2017, he released Couch Baby (Revisited) featuring new track Un-thinkable and remixes from Wiki, Denzel Curry and Rejjie Snow among others.
In January 2018, Jamie announced the title of his next single 'Doing Better' on Instagram and later on posted a video on Twitter in the studio with the caption 'Mastering the album was up till 6am making sure this was perfect I need sleep'.