The season featured a fast-paced gameplay, with double evictions happening every week, until four teen housemates remained for the final.

Kim Chiu was named the series' first "Teen Big Winner" after 42 days of competition against runner-up Mikee Lee and finalists Gerald Anderson, and Clare Cabiguin who placed third and fourth, respectively.

The colours of the walls were changed, and even the living area had a mural with pop art depictions of Mao Zedong, Bruce Lee, and Marilyn Monroe, to name a few.

The prizes for the Big Winner included a condominium unit in Valenzuela City, a livelihood showcase, one million pesos, and an all-expense-paid trip to any Philippine destination.

The twelve initial housemates were introduced in the grand welcome party on Day 1, April 23, 2006, near the facade of the Pinoy Big Brother house.

The Fourth and Third Big Placers received a cash prize of PhP 100,000, a college scholarship and a trip to a local destination.

The Second Teen Big Placer received a cash prize of PhP 500,000, a college scholarship and a trip to a local destination.

The Teen Big Winner received a cash prize of PhP 1,000,000, a college scholarship, a trip to a local destination and a condominium unit to Chatteau Valenzuela.