Meredith attended Hillcrest High School in Simpsonville, South Carolina, where he was a two-way lineman.

Regarded as only a two-star recruit Rivals.com,[1] Meredith was not ranked among the nation's top defensive end prospects.

In his redshirt freshman year, he earned four starts at right tackle, including the 2005 Independence Bowl against Missouri.

He garnered SEC offensive lineman of the week honors after helping the Gamecocks to a 31-28 victory over arch-rival Clemson, in which he anchored an offensive line that held Gaines Adams and the athletic Clemson defensive front without a quarterback sack.

In his senior year, he had to sit out the first two games due to an NCAA eligibility ruling stemming from his freshman season.

He later sat out a couple games with an ankle injury, and played most of the season at left guard.

Meredith was signed off the Green Bay Packers' practice squad by the Buffalo Bills on September 22, 2009 after offensive tackle Brad Butler suffered a season-ending injury.