He was enrolled in 1698 at the Antwerp Guild of Saint Luke as a pupil of Jacob Balthasar Peeters.

[6] A painting by Jan Carel Vierpeyl dated 1721 in the collection of the National Gallery of Ireland, which was believed in the past to depict the philosopher Francis Hutcheson and his daughter, may point to a stay in Great Britain by Jan Carel Vierpeyl.

His standing teenage daughter is holding a book and is pointing to a harpsichord in the room.

The genre works of Vierpeyl are in the style of merry companies and typically depict a group of men and woman engaged in music making, drinking, dancing and courting.

Some of the scenes depict gallant gatherings while others possibly involve courtesans or prostitutes.