Originally classically trained,[1][2] she has released over ten solo albums, often featuring her boogie-woogie piano playing.

[3] Preston has been a member of bands, including Midge Marsden's Country Flyers, Coup D'Etat (with Harry Lyon) and, in Australia, The Tribe.

She sang lead vocals on the Coup D'Etat single No Music on my Radio.

[4] Her work was documented by Sam Neill in the film Red Mole on the Road.

[8] In 2016, Jan Preston broke both of her wrists in an accident; once healed she continued to tour Australia and New Zealand with her band Jan Preston's Boogie Circus.