His most notable position was in the Mughal province of Hyderabad Subah, where he served as its first permanent subahdar (governor) for twelve years, dying in office.
He was the third son of Sayyid Muhammad Sanzwari, a native of Iraq who had migrated to Mughal India in the 17th century (following a stint in the region of Khurasan).
Historian John F. Richards viewed this as indicative of the emperor's trust in Jan Sipar Khan, and theorizes that this may also have been a deliberate move to collect information from the fallen king.
[2] The governor's position in Hyderabad was initially weak, due to a wide series of revolts faced by the Mughal south, which meant that Jan Sipar Khan had limited military resources at this disposal.
For example, in 1691 the province faced a Maratha raid, during which Jan Sipar Khan barricaded himself in the Golconda fort while surrounding villages were looted.