[4] She is also Professor of Molecular Biophysics, a Wellcome Trust Senior Research Fellow[5] in the Department of Chemistry at the University of Cambridge.

Since Clarke was unable to work as a teacher, through not having appropriate qualifications she decided to update her scientific knowledge through a Master of Science degree in applied biology, awarded in 1990 from the Georgia Institute of Technology.

[10] She was subsequently awarded a Doctor of Philosophy degree in 1993 for investigations of Bacterial Ribonuclease (Barnase) from the University of Cambridge supervised by Alan Fersht.

[3] Her nomination for the Academy of Medical Sciences in 2013 reads: Jane Clarke is a distinguished biophysical chemist at the University of Cambridge.

Her certificate of election reads: Jane Clarke is distinguished for the rigorous physical chemistry approaches she has adapted and applied to understand protein folding and misfolding.

Her fundamental studies revealed the presence of both parallel pathways and frustration in the energy landscape of apparently simple proteins.