She has held senior board roles with ANZ Bank, Clayton Utz, the Institute for Health Metrics and Evaluation, the Coalition for Epidemic Preparedness Innovations (CEPI) and Crown Casino.

[6] She and her family moved to Australia in 1973 when her father, Charles Halton, was recruited from Canada by the Whitlam government to lead the Department of Transport.

[8] As a Deputy Secretary in the Department of the Prime Minister and Cabinet, Halton was convener of the People Smuggling Taskforce in the Children Overboard Affair.

During this time, she was responsible for providing advice to government on issues including the administration of Medicare, the Pharmaceutical Benefits Scheme and private health insurance, and for implementing a $60 billion budget.

[15] She identified strengthening the performance framework for measuring the impact of Australian Government programs and services as a priority in the role, with a focus on streamlining and providing a greater level of accountability.

[4] Halton is chair of the global Coalition for Epidemic Preparedness Innovations[24][25] and in March 2020 was appointed to the executive board of the Australian National COVID-19 Coordination Commission.