[2][3][4] She was regarded as a "cheerful, affectionate, and strong woman" with a "gift for storytelling" and as the person from whom Mark Twain inherited his sense of humor.

[12] When Colonel Casey became ill, Lampton learned medical skills from her grandfather, but he died when she was sixteen years old.

As far as her experience went, the wise, the good, and the holy were unanimous in the belief that slavery was right, righteous, sacred, the peculiar pet of the Deity, and a condition which the slave himself ought to be daily and nightly thankful for.

"[18][19][20] The cabin in which the Clemens family is believed to have lived in Fentress County is displayed as part of the collection of the Museum of Appalachia in Norris, Tennessee.

"[28] The influence of Clemens on her son Mark Twain's writings has been the subject of scholarly debate and analysis.

[25][5] There is a display about the life of Clemens at the Mark Twain Birthplace State Historic Site Museum.

[41] Clemens' story is shared in the 2001 Ken Burns documentary Mark Twain, and she is portrayed by a female voice actor in the series.