[5] Levy attended Goucher College in Baltimore, Maryland, for one year, where she played on the Division III varsity women's soccer team.

Levy was named by both TV Guide and TheInsider.com as one of the breakout stars of 2011,[11][12] and was included on the top eleven list of funniest women compiled by AOL.

[16] Levy appeared in two films in 2012: Fun Size, the first feature from Gossip Girl creator Josh Schwartz, and Nobody Walks directed by Ry Russo-Young and written by Lena Dunham.

[17] Levy later starred in the 2013 remake of the horror classic The Evil Dead,[18] as the drug-dependent Mia, replacing Lily Collins, who had originally been cast.

[22] In 2016, Levy teamed up again with Evil Dead director Fede Álvarez, starring in horror film Don't Breathe, which tells the story of three friends breaking into the house of a wealthy blind man.

[25] That same year, she starred with Lucas Till in Monster Trucks, Paramount Animation's first live-action/CGI film, directed by Ice Age's Chris Wedge.

[26][27] In 2017, Levy appeared as Dez in I Don't Feel at Home in This World Anymore directed by Macon Blair,[28] and as Elizabeth in an episode of Showtime series Twin Peaks.

[30] That year, Levy also co-starred with Glenn Close in the Amazon pilot Sea Oak, written by George Saunders and directed by Hiro Murai.