She moved to Nottingham in 1975 to train in paediatrics; in 1976, she became a senior registrar at King's College London and the Royal Alexandra Hospital for Sick Children in Brighton.

[1] She married Simon Currie, a neurologist, in 1976 and they moved together back to Leeds, where Wynne was appointed lecturer in the medical school's paediatrics department and ran a clinic for handicapped children.

She began working with Michael Buchanan, a senior lecturer at the university and an expert in child abuse.

[2] Wynne and her colleague Christopher Hobbs ran courses in Leeds that taught other paediatricians to identify signs of child abuse.

[2] They published two papers on sexual abuse in children in The Lancet in 1986 and 1987, and they founded the Child Protection Special Interest Group in 1988.