Her career started when she was leading praise and worship in her hometown church.

[8] Janet Manyowa released her debut album, King of Glory in August 2015 following the success of the singles Amazing God and Ndomira Pamuri followed by her second album Grateful which was launched in 2017 at the Celebration Centre Auditorium.

The launch event featured prominent South African gospel musicians Dr Tumi, Ntokozo Mbambo and Nqubeko Mbatha who she featured on the song, You Are More.

[9] At the start of 2017, Janet launched a new TV talk show called Redeemed.

[13] In 2020, Janet Manyowa was appointed brand ambassador for ZB Bank Limited and Rainbow Tourism Group, she currently seats as the Board Treasurer of the Zimbabwe Music Rights Association.