Paschal was diagnosed with breast cancer in 2005 and took a year off from touring to undergo chemotherapy and radiation treatments at Duke University Medical Center in Durham, North Carolina.

During her five and a half years with Swaggart, Paschal appeared weekly before 100 million viewers and traveled the world singing at crusades.

[6] Paschal also began her solo career, releasing her first album, titled I Give You Jesus, on Swaggart's ministry label, Shiloh Records, in 1984.

She signed with Word Records and began composing songs such as "Another Soldier's Coming Home", "God Will Make A Way", "The Body and Blood", and "If I'd Had My Way".

[7] She has earned multiple Diamond Awards and numerous Grammy nominations, and she is consistently named among Gospel Music's favorite soloists by the genre's top trade magazines.

[9] In 2009, Paschal started a radio program focused on cancer awareness, Walking The Good Road, that aired on more than 30 stations in the U.S. and Canada.

It is the association's highest award, recognizing trailblazers that have made a profound impact on Christian & gospel music.

Paschal served as the spokeswoman for an international Christian relief organization "Mission of Mercy", founded by missionaries Mark and Huldah Buntain.