I wish all patients a quick recovery.”[7] In his toughest test yet, Alimkhanuly faced former WBA (Regular) champion Rob Brant as the co-featured bout to Vasiliy Lomachenko vs. Masayoshi Nakatani on 26 June 2021 in Paradise, Nevada.

[9] Alimkhanuly faced the former two-time world middleweight champion Hassan N'Dam N'Jikam on 20 November 2021, on the Terence Crawford vs. Shawn Porter undercard.

[18] On 22 September 2022, it was revealed that Alimkhanuly would make a voluntary title defense against the #14 ranked WBO middleweight contender Denzel Bentley.

The title bout was booked as the headliner of an ESPN+ broadcast card, which took place at the Palms Casino Resort in Las Vegas, Nevada, on November 12, 2022.

[22] On 20 November 2022, the WBO formally ordered Alimkhanuly to make a mandatory title defense against the former junior middleweight champion Jaime Munguia.

[25] As Smith was contractually obligated to face Chris Eubank Jr in an immediate rematch, Alimkhanuly instead made his second title defense against the sixth-ranked WBO middleweight contender Steven Butler on 13 May 2023.

[27] Alimkhanuly faced the IBF middleweight titleholder Vincenzo Gualtieri in a championship unification bout on October 14, 2023, at the Fort Bend County Epicenter in Rosenberg, Texas.

[31] Alimkhanuly was scheduled to face Andrei Mikhailovich on July 13, 2024 in Las Vegas, but the bout fell off after he withdrew due to weight cutting issue.

[35][36] Alimkhanuly is scheduled to defend his unified IBF and WBO middleweight titles against Anauel Ngamissengue at Barys Arena in Astana, Kazakhstan on April 5, 2025.