National Route 1 (国道1号, Kokudō Ichi-gō) is a major highway on the island of Honshū in Japan.

When bypasses signed as National Route 1 are included, its total distance increases to 777.9 kilometers (483.4 mi).

[6] The highway's origin and eastern terminus lie at Nihonbashi in Tokyo's Chūō ward.

The highway passes through the cities of Kawasaki, Yokohama, Odawara, Numazu, Shizuoka, Hamamatsu, Nagoya, Yokkaichi, Ōtsu, and Kyoto.

Its endpoint and western terminus lie in the Umeda district of Osaka's Kita ward.