National Route 242 is a national highway of Japan connecting Abashiri, Hokkaidō and Obihiro, Hokkaidō in Japan, with a total length of 284.9 km (177.03 mi).

Route 242 was originally designated on 18 May 1953 from Kushiro to Nemuro.

This was redesignated as Route 44 on 1 April 1963.

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