Completed and commissioned in February 1945, she served during the final months of World War II, conducting a supply run and operating on radar picket duty.

[1] For surface running, the boats were powered by a single 400-brake-horsepower (298 kW) diesel engine that drove one propeller shaft.

[4] Upon commissioning, Ha-105 was attached to the Kure Naval District and assigned to Submarine Squadron 11 for workups.

[4] On 2 November 1945, she was reassigned to Japanese Submarine Division Two under United States Navy command along with her sister ships Ha-103, Ha-106, Ha-107, Ha-108, Ha-109, and Ha-111.

[4] In November 1945, the U.S. Navy ordered all Japanese submarines at Kure, including Ha-105, to move to Sasebo, Japan.

[4] She was among a number of Japanese submarines the U.S. Navy scuttled off the Goto Islands near Sasebo in Operation Road's End on 1 April 1946, sinking at 32°37′N 129°17′E / 32.617°N 129.283°E / 32.617; 129.283 (Ha-105).