Completed and commissioned in August 1945 fours days before hostilities ended in World War II, she surrendered in September 1945 and was scuttled in April 1946.

At the end of 1944, the Imperial Japanese Navy decided it needed large numbers of high-speed coastal submarines to defend the Japanese Home Islands[1] against an anticipated Allied invasion (named Operation Downfall by the Allies).

[1] For surface running, the submarines were powered by a single 400-brake-horsepower (298 kW) diesel engine that drove one propeller shaft.

[2] Upon commissioning, Ha-210 was attached formally to the Sasebo Naval District and assigned to Submarine Division 52.

[2] On 2 November 1945, she was reassigned to Japanese Submarine Division Three under United States Navy command along with her sister ships Ha-201, Ha-202, Ha-203, and Ha-205.