Jarrett Lee Hoffpauir (born June 18, 1983) is an American former professional baseball second baseman.

Hoffpauir was drafted by the St. Louis Cardinals in the 6th round of the 2004 Major League Baseball Draft from the University of Southern Mississippi following his junior year, during which he hit .405 with 92 RBI and was named to the All-Conference Tournament Team.

Jarrett was claimed off waivers by the Toronto Blue Jays on November 3, 2009 On April 25, 2010, he hit for the cycle for Triple-A Las Vegas against Sacramento, going 4–5.

On June 20, 2010, the Blue Jays purchased Hoffpauir's contract and optioned Edwin Encarnación to Las Vegas.

After becoming a free agent, Hoffpauir signed a minor league contract with the Blue Jays on January 25, 2013, but was released soon after.