[1] While in intensive care, Benetti developed a respiratory illness that deprived his blood of oxygen; this may have caused his cerebral palsy, which was diagnosed when he was a toddler.

[8] Benetti attended S. I. Newhouse School of Public Communications at Syracuse University and graduated in 2005 with bachelor's degrees in broadcast journalism, economics and psychology.

[11] After graduating from Syracuse, Benetti enrolled at Wake Forest University School of Law, where he earned a Juris Doctor degree in 2011.

[4][12] He also worked in roles with Fox Sports 1, Westwood One, Big East Conference, IMG College, Salem Avalanche, and DePaul University.

[13] Beginning with the 2016 season, Benetti replaced recently retired Hall of fame broadcaster Ken Harrelson as the television play-by-play announcer for select Chicago White Sox home and road games, where he would be paired with Steve Stone.

[26] In week 17 and 18 of the 2022 NFL season, Benetti would work his first games for the NFL on Fox, doing play-by-play as the Arizona Cardinals visited the Atlanta Falcons to start, followed by the Carolina Panthers against the New Orleans Saints in week 18 and filled-in for Brandon Gaudin, who filled-in for Wayne Larrivee on the Green Bay Packers radio network.

[27] Benetti works with the CHAT ("Communication Hope through Assistive Technology") Camp at Syracuse University's Burton Blatt Institute.