[2] Ambrossi graduated with a degree in journalism from the Complutense University of Madrid and studied dramaturgy at the Real Escuela Superior de Arte Dramático.
[9] From October 2017 to February 2018, Ambrossi and Calvo appeared on the reality television talent competition show Operación Triunfo as the teachers of acting in the "Academy".
[11] The series narrates the life of actress, celebrity, model, sex worker, and star, Cristina Ortiz, la Veneno, who was one of the first women to bring visibility to the trans community in Spain during the nineties and is based on Valeria Vegas's ¡Digo!
[12] When the first three episodes were released, they landed at the top of Spain's box office, and subscribers to Atresplayer increased by 42% with the show, which is watched ten times more than any other on the platform.
[17] In 2023, the family thriller television series La mesías, created, written and directed by Ambrossi and Calvo for Movistar Plus+, was included out of competition in the official section of the 71st San Sebastián International Film Festival.
[18] Centered around the life of a man named Enric, who carries religious childhood trauma, the series is about how he is impacted by the viral video of a Christian pop music group, and it has been described as their most ambitious and complex project to date.
[20] The show begins two years after Veneno when Valeria returns to Valencia and discovers a VHS copy of Antonio Giménez Rico's famous documentary Vestida de azul and looks to uncover what has happened to the six transgender women it features.
"With the series, we’d like to convert the documentary’s protagonists into a mainstream phenomenon, giving them what they didn’t have in the past: Fame but also respect and affection," Ambrossi has explained.
There work has been described as "representative of a Spanish queer aesthetics which navigates between combative subversion and mainstream normalization" and as "changing hegemonic social and idealogical constructs in relation to gender, sexuality, and identity".