He won 1996 French Open mixed doubles title with compatriot Patricia Tarabini.

He reached his career-high ATP singles ranking on July 24, 1995, when he became world No.

Frana debuted at the Seoul Olympics in 1988, where he was defeated in the second round by fellow countryman Martín Jaite, 2–6, 4–6 and 2–6.

At the 1992 Olympics in Barcelona, he reached the second round again, this time falling to France's Fabrice Santoro, 6–4, 2–6, 1–6, and 1–6.

He represented his native country for the last time in Olympic competition at the 1996 Summer Olympics in Atlanta, United States, where he was defeated in the first round by Great Britain's Greg Rusedski.