Jean-Baptiste Dominique Rusca (French pronunciation: [ʒɑ̃ batist dɔminik ʁyska]; 27 November 1759 – 14 February 1814) was born in the County of Nice, part of the Kingdom of Sardinia.

By profession a medical doctor, he advocated the cause of the French Revolution and was expelled by the Sardinian authorities.

In 1793, he treated the French sick and wounded during the Siege of Toulon and was appointed to command a sapper battalion.

By the time of the Montenotte Campaign in 1796, he was a general officer leading major units.

After commanding garrisons for several years, he led a division in Italy during the 1809 war.