Jean-Luc Moudenc (French: [ʒɑ̃ lyk mudɛ̃k]; Occitan: Joan Luc Modenc [dʒwan ˈlyk muˈðeŋk]; born 19 July 1960) is a French politician serving as Mayor of Toulouse since 2014, previously holding the office from 2004 to 2008.

A member of The Republicans, he was defeated for reelection in 2008 by Pierre Cohen, candidate of the Socialist Party.

He became a municipal councillor in 1987, before entering the Regional Council of Midi-Pyrénées in 1992, where he stayed until 2004.

After the elevation of Mayor Philippe Douste-Blazy to the position Minister of Health, an interim officeholder was appointed in the person of Françoise de Veyrinas.

Moudenc is standing for reelection in the 2020 municipal election with the support of Les Républicains and La République En Marche!