[3] She served as president of the Delta Sigma Theta (DST) sorority within which she founded that group's National Commission on Arts and Letters.

Noble was the first African-American board member of the Girl Scouts of the USA, and the first to serve the U.S. government's Defense Department Advisory Committee on Women in the Services (DACOWITS).

She headed the Women's Job Corps Program in the 1960s, and was the first African-American woman to be made full professor at the New York University's Steinhardt School of Culture, Education, and Human Development.

[3] Noble wrote several books including The Negro Woman's College Education and Beautiful, Also, Are the Souls of My Black Sisters.

With a grant from Pi Lambda Theta, she studied black college women and analyzed data relative to their backgrounds, educations, and achievements.

[5] Other lecturer positions Noble held during her career included summer visiting professorships at the University of Vermont and at the Tuskegee Institute.

From 1958 to 1963 Noble was the national president of the Delta Sigma Theta sorority, a public service organization she joined while an undergraduate at Howard University.

She was also on the board of directors of the Urban League of Greater New York, the Girl Scouts of the US, and the National Social Welfare Assembly.

[4] In 1964, President Lyndon B. Johnson tapped Noble to help him plan the Women's Job Corps, a program of his announced War on Poverty.

She worked for five months on a 40-page plan to increase jobs for girls and women aged 16 to 21; a demographic that was vulnerable and in great need of employment.

Around 1975 Noble moved from NYU to Brooklyn College of the City University of New York where she taught in the education department, eventually becoming a professor of guidance and counseling in the graduate school.

She won a regional Emmy Award for her New York-area television program The Learning Experience which she wrote and moderated; it aired weekly on WCBS-TV in the 1970s.

The institute was conceived to foster a cadre of young leaders to assist traditional African-American women's organizations to meet the challenges of the 21st century.