Jeffers is an unincorporated community and census-designated place (CDP) in Madison County, Montana, United States.

It is in the eastern part of the county, on the east side of the valley of the Madison River.

By road it is 2 miles (3 km) east of Ennis, which sits on the west side of the river.

Jeffers was first listed as a CDP prior to the 2020 census, when it had a population of 25.

This Madison County, Montana state location article is a stub.