The Jefferson City metropolitan statistical area, as defined by the United States Census Bureau, is an area consisting of four counties – Cole, Callaway, Moniteau, and Osage – in central Missouri anchored by the city of Jefferson City.

[2] The Jefferson City MSA consists of four counties, and borders the Columbia metropolitan area to the north.

As of the census[3] of 2000, there were 140,052 people, 51,637 households, and 35,569 families residing within the MSA.

The racial makeup of the MSA was 90.12% White, 7.12% African American, 0.38% Native American, 0.64% Asian, 0.03% Pacific Islander, 0.52% from other races, and 1.19% from two or more races.

Males had a median income of $29,922 versus $22,678 for females.