Jefferson Heights is a hamlet and census-designated place (CDP) in Greene County, New York, United States.

Jefferson Heights is located in southeastern Greene County at 42°14′7″N 73°52′34″W / 42.23528°N 73.87611°W / 42.23528; -73.87611 (42.235394, -73.876021),[4] in the northeastern part of the town of Catskill.

New York State Route 23 is a four-lane highway through the northern part of Jefferson Heights, leading east to the Rip Van Winkle Bridge over the Hudson River and northwest 8 miles (13 km) to Cairo.

Interstate 87, the New York State Thruway, runs along the northwest border of Jefferson Heights, and Thruway Exit 21 (Cairo – Catskill - NY Route 23) is in the northern part of the CDP.

[2] Catskill Creek, a tributary of the Hudson River, forms the southern and western edge of the CDP, and Hans Vosen Kill, a tributary of Catskill Creek, forms the eastern edge.