Jefferson Partners also conducts charter bus service within Minneapolis and Billings for large group travel.

[2] The company's name originates from the Jefferson Highway, a north–south route in the early National Auto Trail system that once ran from Winnipeg, Manitoba, Canada, south to New Orleans, Louisiana.

The court ruled in favor of the state, effectively overturning the precedent that it had set in 1948 in Central Greyhound Lines, Inc. v. Mealy.

Jefferson Lines has taken over operation of many former Greyhound routes and improved ridership significantly on some of them.

The service to Winnipeg was cut back to Grand Forks, North Dakota, on October 7, 2010.

Before his career at Jefferson, Woelfel was vice president and general manager of Fox Sports Net North.

Charlie had been an investment banker in New York City until returning to Minnesota in 1987 to take over the company from his late father, Louie.