[3] Palmieri's family frequently moved growing up due to her father's career in the US Navy, ultimately settling in California when she was 11.

She served in the Clinton Administration as Special Assistant to White House Chief of Staff Leon Panetta, then deputy director of Scheduling and Advance, and finally as a Deputy White House Press Secretary the last three years of Clinton's presidency.

[7] Palmieri attracted controversy when an email chain allegedly showing Clinton aides joking about Catholics and evangelicals in 2011 was released by WikiLeaks.

[11][10] In the emails between Palmieri, Podesta, and John Halpin of the Center for American Progress, Halpin reportedly wrote that 21st Century Fox Chairman Rupert Murdoch and NewsCorp Chief Executive Robert Thomson were drawn to Catholicism because of the faith's "systemic thought and severely backward gender relations.

"[16][17][18] At a Harvard University forum held on December 1, 2016, to define the Clinton Campaign for the historical record, Palmieri ascribed the loss to (1) alleged white supremacists within the Trump campaign, (2) the e-mail scandal (which she believed reporters should not have covered), and (3) claimed "[that] many political journalists had a personal dislike for the Democratic nominee.