In September 2011, De Nooijer received his first call into the Sparta Rotterdam senior squad, when he was an unused substitute for a 1–0 Eerste Divisie win over Den Bosch.

He left Sparta at the end of the 2014–15 campaign making a total of 62 league appearances, scoring two goals.

On 29 June 2015, De Nooijer signed a two-year contract with Bulgarian side Levski Sofia.

On 5 March 2019, de Nooijer joined Lithuanian club FK Sūduva Marijampolė.

[2] In June 2019, de Nooijer signed a one-year contract with Qatari club Al-Shamal SC, with an option for another year.