Jerome de Salis, Count de Salis-Soglio, DL, JP, FRS (14 February 1771 – 2 October 1836), Illustris et Magnificus, was an Anglo-Grison noble and Irish landowner.

[citation needed] Born in Chiavenna on 14 February 1771, he died on 2 October 1836 at Dawley Lodge, Harlington, and lies buried in the ancient church of St Peter and St Paul, Harlington, London, which was at the time in Middlesex.

In a letter of 1830 he proposed spending the winter in Madeira whence: De Salis was a friend of Samuel Wix, the high-churchman, and paid for his Reflections concerning the expediency of a council of the Church of England and the Church of Rome being holden, with a view to accommodate religious differences (1818) to be translated into several languages.

His first marriage was to Sophia (1765 – 14 June 1803), daughter of Admiral Francis William Drake (1724–87), himself the brother of Sir Francis Henry Drake, 5th and last Baronet.

The couple were married on 12 August 1797 at Shirburn Castle, and had: Four years after Sophia's death in 1803, De Salis married Penelope (died 20 December 1807), daughter of Dr. Robert Freeman, MD, of Uxbridge, on 14 March 1807 in Stoke Poges, and had one daughter.