He was assigned to the Japanese mission and left Lisbon in April 1596, in company with 7 other Jesuits destined for Japan.
Storms disrupted his journey and took him to Brazil, Puerto Rico and England (after being captured by an English ship).
[3] He set out again in 1599 with Charles Spinola and three others, bound for the College in Goa, to complete his studies in anticipation of ordination.
De Angelis, after making many converts to Christianity, seeing that his neophytes were cruelly persecuted because of his presence among them and his preaching, gave himself up to the authorities in 1623.
Condemned to death, he underwent public execution by fire on 4 December 1623 during the Great Martyrdom of Edo.