The next year Sisemore blossomed into one of the nation's best linemen as he had the first of two consecutive seasons (1971 and 1972) where he was both an all-conference and Unanimous All-America selection.
In his 1972 senior year, Texas won its fifth consecutive Southwest Conference title and gained its dfourth straight Cotton Bowl Classic bid.
Sisemore was the 3rd pick in the 1973 NFL draft and was an impact player with the Philadelphia Eagles, especially after the arrival of legendary coach Dick Vermeil in 1976.
Sisemore was a big part of an offense that featured Philadelphia sports legends such as quarterback Ron Jaworski and running back Wilbert Montgomery.
Sisemore moved to Lago Vista, Texas where he opened a marina on Lake Travis and became a real estate agent.