Raffin made his debut in the Moto2 World Championship in 2012 with GP Team Switzerland as a replacement for the injured Randy Krummenacher;[1] in three races he had an 18th place at Sepang as best finish.

He failed to score championship points, as his best result was 17th place, obtained in third occasions—Indianapolis, Motegi and Phillip Island.

In 2017, Raffin switched to the Garage Plus Interwetten team from his home country Switzerland.

In 2019, Raffin joined the inaugural MotoE World Cup with the German Dynavolt Intact GP team.

Having impressed in his replacement entries with RW, Raffin was signed by the team to make his full-time return to Moto2 for 2020.