As Chief White House correspondent she conducted an in-depth interview with President Barack Obama that aired throughout the Democratic Convention and helped shape the network's coverage.

[11] She provided breaking news and analysis on President Obama's administration, and during the 2012 election interviewed Secretary of State Hillary Clinton, First Lady Michelle Obama, former White House Chief of Staff Rahm Emanuel, House Speaker John Boehner, and former top economist Larry Summers.

Yellin has also covered significant policy debates in Washington, including the push to reform the financial regulatory system.

She began with ABC in July 2003 and reported on politics and culture for such programs as Good Morning America and Nightline.

Prior to this, she served as front-of-the-book editor at Los Angeles Magazine, where she contributed and edited stories on politics, Hollywood, and cultural issues.

[21] In 2009, Jessica received a Gracie Award from the Alliance for Women in Media for her coverage of the 2008 presidential campaign.

[25] In 2011, Jessica was part of a team of CNN journalists who received an Emmy Award for their coverage of the Gulf oil spill.

In 2017, Jessica was named one of Forbes’ “Most Powerful Women in Media.” The list recognizes the most influential and accomplished women in the media industry, and Jessica's inclusion on the list was a testament to her impact and influence as a journalist Yellin is a senior fellow at the USC Annenberg School of Journalism and a member of the Board of Directors for the Center for Public Integrity.