Schram modeled and appeared in television commercials as a child, and began performing in musical theatre at age 12.

[5] Her first on-screen appearance was a role as Larissa in the episode "Number One Fan" of Nickelodeon's sitcom Drake & Josh.

[6][7] She has appeared in several guest starring television roles, including CSI: Miami, Without a Trace, House, Ghost Whisperer, Medium, The Mentalist and Boston Legal.

[8] Schram appeared in Tony Scott's action thriller film Unstoppable (2010), playing Darcy, the estranged wife of Chris Pine's character.

[10] She landed a role as Jennifer in crime thriller film Shot Caller (2017), which received generally positive reviews from critics.