The 1950 Jesup Bees first began play as an expansion team, joining as members of the eight–team Class D level Georgia State League.
The Bees finished with a record of 69–69 in the 1950 Georgia State League standings, playing under manager Herb Stein.
The Jesup Bees finished with a record of 52–73, playing under returning manager Donald Stoyle and player/manager James Warren.
[8][9] In their final season of play, the Jesup Bees won the 1953 Georgia State League pennant.
After the 1953 season, both the Jesup and Eastman franchises folded, leaving the 1954 Georgia State League with six teams.