He served as a voice actor in several animated series, films, and video games, and is best known for portraying Angelo Bronte in Red Dead Redemption 2, Luca Cocchiola in Battlefield 1, Rais in Dying Light, Boozer in Days Gone, and Kraven the Hunter in Spider-Man 2.
He has also acted on TV shows such as David Vega in Victorious and Uncle Frank in Shake It Up.
In 2016, he portrayed Commander Akeel Min Riah in Call of Duty: Infinite Warfare.
In 2019, he portrayed William "Boozer" Gray, best friend of protagonist Deacon St. John, in Days Gone.
In May 2023, Pirri confirmed at the time of the release of the newest trailer and gameplay footage for Marvel’s Spider-Man 2 at the 2023 PlayStation Showcase that he had obtained the role of Kraven the Hunter.