[2] After he'd finished high school, he then continued his education at the Faculty of Communication Arts at Rangsit University, in the field of radio and television broadcasting.

[4] James Jirayu learned how to dance and sing at a young age and he even had his own band, where he played bass guitar in high school.

[5][6] ศ.ศ.2006 เจมส์ประกวดเดอะสตาร์ 3 เป็นตัวแทนภาคกลาง-ใต้ ศ.ศ.2010 จิรายุได้เข้าร่วมสมาชิกกามิกาเซ่ เคลือของอาร์เอส In April 2012, Charnchalard Dhaweesap, the owner of an entertainment agency called "Meta Talent Management", saw James' photos on Facebook and scouted him.

In September, he starred, for the first time, in a movie called First Love and two other dramas Thong Neu Gao (Angel Heart) and Ruk Sudrit (Race).

[10] In September, he appeared on the stage of Tokyo Girls Collection (TGC) 2015 Autumn/Winter as a guest when he traveled to Japan for 2 months to take singing and dancing lessons.

At the end of 2015, he returned to Vietnam to take a martial arts class at Johnny Tri Nguyen's Lien Phong Academy in preparation for his new drama Padiwaradda (The Loyal Wife), as the lakorn featured many action scenes.

In the same month, CH3 broadcast the TV show, Tabi Japan with James Jirayu, focusing on the six prefectures of Tohoku region.

He performed as a model on the stage of Yohji Yamamoto 2016–17, Autumn-Winter Paris Men's Collection.

[13] In March, his first drama with Kimberley Anne Woltemas, titled Buang Hong (Fallen Angel) aired.

In April, he appeared on the Tokusatsu series, Idol x Warrior Miracle Tunes!, broadcast by TV Tokyo as "Demon King".

[17] In June 2018, it was confirmed that James and Preechaya Pongthananikorn would star in the lakorn Prayakorn Sorn Ruk (Prophecy of Love), directed by Yuttana Lorpanpaiboon.

In the beginning of 2019, he started filming his new drama Leh Banpakarn (Mist of Love) with Natapohn Tameeruks.

His role, "Ah-Sa", in Krong Kam (Repercussion), airing from February 26 to April 30, 2019, has resulted in intense adoration of him.