Mukherjee was born on 23 April 1893 to a Kulin Brahmin family of Kannaujite descent in the village of Mahadevpur in Rajshahi District, Bengal Presidency (now Bangladesh).

Based on his thesis for MSc Degree a paper on Electric Synthesis of Colloids was published in the Journal of the American Chemical Society (1915,39,292).

In 1919 he and Jnan Chandra Ghosh joined the University College, London to work in the Physical Chemistry Laboratory under the charge of Professor FG Donnan, FRS.

Professor Mukherjee continued his research on colloids and his major line of work was to develop his theory of the electrokinetic double layer and its ionic constitution.

[2] Besides making pioneering contribution in the domain of Soil Science, Dr Mukherjee played a key role in the development of agricultural research and education in the country.

The terms and reference of the Committee were practically in conformity with the objectives of the All India Soil and Land Use Survey Organization established in 1956 with 4 regional centres.

In 1958, on the recommendation of the Indo-American Team on Agricultural Research and Education and with the generous aid of the Rockefeller Foundation, the Post-Graduate School was established at this Institute by the Governmental of India.

Some of them are: Professor of Chemistry, University College of Science and Technology, Calcutta Director, Indian Agricultural Research Institute founder Director"; Central Building Research Institute, Roorkee; Part-time Scientific Adviser, Departments of Agriculture, Animal Husbandry, Irrigation, Forest, Community Development, Government of West Bengal; Administrator, Boardof Secondary Education, West Bengal; Member.