In October 2012, an anime television series produced by David Production adapting Phantom Blood and Battle Tendency began broadcast on Tokyo MX.

JoJo's Bizarre Adventure is well-known for its art style and poses, frequent references to Western popular music and fashion, and battles centered around Stands, psycho-spiritual manifestations with unique supernatural abilities.

Each of the series' protagonists is a member of the Joestar family, whose mainline descendants possess a star-shaped birthmark above their left shoulder blade and a name that can be abbreviated to the titular "JoJo".

However, Araki did not want Part 3 to be a tournament affair, which was popular in Weekly Shōnen Jump at the time, and therefore decided to make it a "road movie" inspired by Around the World in Eighty Days.

[20] A sōshūhen omnibus series recreating the first four parts as they originally appeared in Weekly Shōnen Jump (including color pages, promotional text, and next chapter previews) was published between 2012 and 2016.

A tankōbon volume was published by Shueisha in November 2013, collecting the stories "At a Confessional", "Mutsu-kabe Hill", "Millionaire Village", "Poaching Seashore", and "Rohan Kishibe Goes to Gucci".

[40] In the September 2021 issue of Ultra Jump, it was announced that JoJo's Bizarre Adventure would be receiving a spin-off manga written by Kouhei Kadono and illustrated by No Guns Life author Tasuku Karasuma.

also produced JoJo's Bizarre Adventure: Phantom Blood, a feature film adaptation of the manga's first arc; it was released theatrically in Japan on February 17, 2007.

[42] At a July 2012 press conference celebrating the 25th anniversary of the series, Araki announced that an anime adaptation of JoJo's Bizarre Adventure was in production and would premiere in October 2012.

[50] An original video animation (OVA) based on the "Millionaire Village" episode of the Thus Spoke Rohan Kishibe spin-off manga was distributed in 2017 to those who purchased every DVD or Blu-ray volume of Diamond Is Unbreakable.

[54] With the 2014 premiere of Stardust Crusaders, American-based website Crunchyroll began streaming the anime series for viewers outside Japan one hour after the episodes aired.

The first was titled A Ghost Story from Budogaoka High[h] and the second After-school Talk: At Cafe Deux Magots..[i] Several video games based on the series have been created.

The first, based on Part 3, was simply titled JoJo's Bizarre Adventure, released on November 4, 1993, and written by Mayori Sekijima and Hiroshi Yamaguchi.

[61] Le Bizzarre Avventure di GioGio II: Golden Heart/Golden Ring,[j] written by Gichi Ōtsuka and Miya Shōtarō and based on Part 5, was released on May 28, 2001.

[83] Reviewing the first volume, IGN named JoJo's Bizarre Adventure a "must read", declaring the artwork of "a standard virtually unseen in most manga produced today.

[85] Rebecca Silverman of Anime News Network wrote that the first volume "combines a fighting story with a solid emotional background, and will absolutely put hair on your chest."

"[86] Comics & Gaming Magazine's Cole Watson also strongly praised Dio as the highlight character of Part 1, stating that his eyes were glued to the page whenever he appeared, and described him as "the literal embodiment of Satan in manga form."

Watson gave Phantom Blood a 7.5 out of 10, writing that while there is a lot to enjoy, it primarily serves as Dio's origin story and there are some moments that are "agonizingly slow".

[91] She initially called the replacement of Hamon with Stands both understandable and a bit of a disappointment, since the "insane physical abilities and contortions" caused by the former were a large source of the fun in the first two parts.

"[94] Both Screen Rant's Steven Blackburn and Jordan Richards of AIPT Comics called Golden Wind a breath of fresh air for JoJo's Bizarre Adventure by deviating from the basic formula and following Giorno, son of villain Dio Brando, as he looks to cement a reputation and build a criminal empire.

[95][96] Jenni Lada of Siliconera also praised the protagonist Giorno and said the first volume of Part 5 shows how skilled Araki is at getting people quickly invested in a character and story.

[98] For the 10th anniversary of the Japan Media Arts Festival in 2006, Japanese fans voted JoJo's Bizarre Adventure second on a list of the Top 10 Manga of all time.

[102] In November 2014, readers of Da Vinci magazine voted JoJo's Bizarre Adventure as the fifth Weekly Shōnen Jump's greatest manga series of all time.

halted manga/OVA shipments of JoJo's Bizarre Adventure after a complaint had been launched against them from anonymous online Egyptian Islamic fundamentalists, after noticing a scene in the OVAs that has the villain, Dio Brando, reading a book depicting pages from the Qur'an.

[109] Araki contributed JoJo-inspired art for Sayuri Ishikawa's 2012 album X -Cross-, where she performs one of the series' iconic poses and is drawn wearing jewelry from the manga.

[110] JoJo-style artwork has also been produced for other literature, such as for a 2008 collection featuring Yasunari Kawabata's short story "The Dancing Girl of Izu"[111] and a 2012 reprint of Tamaki Saitō's Lacan for Surviving.

[116] From July 19 to August 18, 2019, the Tower Records store in Shibuya held an exhibit celebrating the finale of the fifth part of the series, Golden Wind, and to promote the release of two games, JoJo's Bizarre Adventure: Pitter Patter Pop!

[124] The exhibit celebrated the 90th anniversary of Gucci and featured a life-size figure of Rohan Kishibe, as well as numerous illustrations by Araki that included actual pieces of the brand's own 2011–2012 fall/winter collection and his own original fashion designs.

[135][137] The October 2012 issue of Ultra Jump contained a special booklet titled 25 Years With JoJo that also celebrated the anniversary; it featured messages and tribute art from well-known manga artists such as Akira Toriyama, Yoshihiro Togashi, Eiichiro Oda, Clamp, and 18 others.

[140] To celebrate the release of the All Star Battle video game created for the 25th anniversary, a special JoJo-themed train traveled the Yamanote Line in Tokyo from August 29 to September 9, 2013.